| Inherited metabolic disorders |
| Allogeneic (with immunosuppression or tolerization) |
| Autologous with ex-vivo gene transfer |
| Acute liver failure |
| As a "bridge" while awaiting liver transplantation |
| As definitive therapy in selected cases |
| Chronic liver failure |
| For improving metabolic function and encephalopathy |
| To "buy time" while awaiting liver transplantation |
| Rescuing patients who require curative doses of hepatic irradiation |
| As a part of treatment |
| Generating animal models |
| For human hepatocyte-specific infections by transplanting human hepatocytes into immunodeficient animals |
