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Uptodate Reference Title
Women's Health Initiative: Risk of stroke
Women's Health Initiative: Risk of stroke
Kaplan-Meier estimates of cumulative hazard rates of stroke. In the Women's Health Initiative, combined estrogen-progestin therapy was associated with a significant increase in stroke when compared with placebo. The intention-to-treat hazard ratio was 1.31, 95% CI 1.02-1.68.
Data from: Wassertheil-Smoller S, Hendrix SL, Limacher M, et al. Effect of estrogen plus progestin on stroke in postmenopausal women: The Women's Health Initiative: A randomized trial. JAMA 2003; 289:2673.
