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Ideal lung transplant donor criteria*

Ideal lung transplant donor criteria*
Age <55 years
ABO compatibility
Clear chest radiograph
PaO2 >300 on FiO2 = 1.0, PEEP - 5 cm H2O
Tobacco history <20 pack years
Absence of significant chest trauma
No evidence of aspiration/sepsis
No prior cardiopulmonary surgery
Acceptable bronchoscopic inspection without evidence of aspirated stomach contents or purulent secretions
Gram stain of sputum/BAL without organisms
No history of significant chronic lung disease
FiO2: fraction of inspired oxygen; PaO2: partial pressure of arterial oxygen; PEEP: positive end-expiratory pressure; BAL: bronchoalveolar lavage.
* These criteria describe "ideal" lung transplant donors, but most lung donors do not meet all of these criteria. Thus, all potential donors should be discussed with the organ procurement organization (OPO) and lung transplant team to determine acceptability.
Adapted with permission from: Bhorade, SM, Vigneswaran, W, McCabe, MA, Garrity, ER. Liberalization of donor criteria may expand the donor pool without adverse consequence in lung transplantation. J Heart Lung Transplant 2000; 19:1199. Copyright © 2000 Elsevier.
Updated from:
  1. Kotloff RM, Blosser S, Fulda GJ, et al. Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement. Crit Care Med 2015; 43:1291.
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