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Connection between osteocytes and blood vessels

Connection between osteocytes and blood vessels
The connection between osteocytes and blood vessels.
(A) Low (upper panel) and high (lower panel) magnifications of electron microscopy images demonstrating reliefs of the osteocytes and their canalicular network following acid-etching of murine bone sections (Courtesy of Lynda Bonewald from the University of Missouri and Kansas City Dental School). Please note multiple attachments of the osteocyte processes to the vessels depicted in the center of these images.
(B) Cartoon depicting the same connections.
Reproduced with permission from: Manolagas SC. From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis. Endocr Rev 2010; 31:266. Copyright © 2010 The Endocrine Society.
Graphic 73524 Version 2.0