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Toronto Side Effects Scale

Toronto Side Effects Scale
Patient name: Date:

Within the last two weeks, have you had any of the symptoms listed below?

How much trouble did each symptom cause you?

For each symptom, mark how often (frequency) and how bothersome (severity) it is in the boxes below.
Symptom Frequency   Severity
Never
1		 Sometimes
2		 About half the time
3		 Often
4		 Every day
5		 No trouble
1		 Some trouble
2		 Moderate trouble
3		 More trouble
4		 Extreme trouble
5
Nervousness 1 2 3 4 5 1 2 3 4 5
Agitation 1 2 3 4 5 1 2 3 4 5
Tremor 1 2 3 4 5 1 2 3 4 5
Twitching/myoclonus (muscle contraction) 1 2 3 4 5 1 2 3 4 5
Abdominal pain 1 2 3 4 5 1 2 3 4 5
Dyspepsia (upset stomach) 1 2 3 4 5 1 2 3 4 5
Nausea 1 2 3 4 5 1 2 3 4 5
Diarrhea 1 2 3 4 5 1 2 3 4 5
Constipation 1 2 3 4 5 1 2 3 4 5
Decreased appetite 1 2 3 4 5 1 2 3 4 5
Increased appetite 1 2 3 4 5 1 2 3 4 5
Weakness or fatigue 1 2 3 4 5 1 2 3 4 5
Dizziness 1 2 3 4 5 1 2 3 4 5
Postural hypotension (dizzy when getting up) 1 2 3 4 5 1 2 3 4 5
Drowsiness/daytime somnolence 1 2 3 4 5 1 2 3 4 5
Increased sleep 1 2 3 4 5 1 2 3 4 5
Decreased sleep 1 2 3 4 5 1 2 3 4 5
Sweating 1 2 3 4 5 1 2 3 4 5
Flushing 1 2 3 4 5 1 2 3 4 5
Edema (fluid retention) 1 2 3 4 5 1 2 3 4 5
Headache 1 2 3 4 5 1 2 3 4 5
Blurred vision 1 2 3 4 5 1 2 3 4 5
Dry mouth 1 2 3 4 5 1 2 3 4 5
Anorgasmia/no orgasm 1 2 3 4 5 1 2 3 4 5
Increased libido 1 2 3 4 5 1 2 3 4 5
Decreased libido 1 2 3 4 5 1 2 3 4 5
Other, specify: 1 2 3 4 5 1 2 3 4 5
Weight gain None ≤2 lb ≤4 lb ≤6 lb ≤7 lb 1 2 3 4 5
Weight loss None ≤2 lb ≤4 lb ≤6 lb ≤7 lb 1 2 3 4 5
Men only Men only
Premature ejaculation 1 2 3 4 5 1 2 3 4 5
Delayed ejaculation 1 2 3 4 5 1 2 3 4 5
Erectile dysfunction 1 2 3 4 5 1 2 3 4 5
  • Patient instructions: Circle the number for frequency and the number for severity that best describes the side effect.
  • Physician instructions: An "intensity" score is derived by multiplying frequency score by severity score. Use the intensity score to track the progress of your patient's side effects.
Reproduced with permission from: Vanderkooy JD, Kennedy SH, Bagby RM. Antidepressant side effects in depression patients treated in a naturalistic setting: A study of bupropion, moclobemide, paroxetine, sertraline, and venlafaxine. Can J Psychiatry 2002; 47:174. Copyright © 2002 Canadian Psychiatric Association.
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