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Tubuloglomerular feedback

Tubuloglomerular feedback
Relationship of single-nephron GFR to distal nephron (macula densa) perfusion rate in dogs. As the perfusion rate increases (via insertion of a micropipette into the late proximal tubule), there is a progressive reduction in GFR to a minimum of about one-half the basal level.
GFR: glomerular filtration rate.
Data from Navar LG. Renal autoregulation: perspectives from whole kidney and single nephron studies. Am J Physiol 1978; 234:F357.
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