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Mortality after thrombolytic therapy is lower with complete ST segment resolution

Mortality after thrombolytic therapy is lower with complete ST segment resolution
In four studies of thrombolytic therapy for an acute myocardial infarction, the degree of ST segment resolution at 180 min after administration of therapy was associated with 35-day mortality. All studies found statistically significant mortality differences between the three groups of ST resolution.
GUSTO-III: Global Use of Strategies to Open Occluded Coronary Arteries study; HIT-4: Hirudin for Improvement of Thrombolysis (HIT)-4 study; INJECT: International Joint Efficacy Comparison of Thrombolytics study; ISAM: Intravenous Streptokinase in Acute Myocardial Infarction.
Data from de Lemos JA, Braunwald E. J Am Coll Cardiol 2001; 38:1283.
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