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Algorithm for FISH in assessment of HER2 status

Algorithm for FISH in assessment of HER2 status
FISH: fluorescence in situ hybridization; HER2: human epidermal growth factor receptor 2; IHC: immunohistochemistry; CEP17: chromosome 17 centromere.
Revised with information from:
  1. Wolff AC, Hammond ME, Hicks DG, et al. Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update. J Clin Oncol 2013. DOI: JCO.2013.50.9984.
Modified from: Wolff AC, Hammond EH, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Onc 2007; 25:118. Copyright © 2007 American Society of Clinical Oncology.
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