| Fever |
| Hypotension |
| Acute phase protein response |
| Induction of IL-6 and IL-8 |
| Coagulation activation |
| Fibrinolytic activation |
| Leukocytosis |
| Neutrophil degranulation and augmented antigen expression (TNF) |
| Increased endothelial permeability (TNF) |
| Stress hormone response |
| Enhanced gluconeogenesis (TNF) |
| Enhanced lipolysis (TNF) |
