| Mild | Moderate | Severe | |
| Pancreatitis | Amylase at least three times normal at more than 24 hours after the procedure, requiring admission or prolongation of planned admission to two to three days | Hospitalization of 4 to 10 days | Hospitalization of more than ten days, hemorrhagic pancreatitis, phlegmon or pseudocyst, or intervention (percutaneous drainage or surgery) |
| Bleeding | Clinical (not just endoscopic) evidence of bleeding, hemoglobin drop <3 g, and no need for transfusion | Transfusion (four units or less), no angiographic intervention or surgery | Transfusion (five units or more) or intervention (angiographic or surgical) |
| Cholangitis | Temperature of >38°C for 24 to 48 hours | Febrile or septic illness requiring more than three days of hospital treatment or endoscopic or percutaneous intervention | Septic shock or surgery |
| Perforation | Possible, or only very slight leak of fluid or contrast, treatable by fluids and suction for three days or less | Any definite perforation treated medically for 4 to 10 days | Medical treatment for more than 10 days, or intervention (percutaneous or surgical) |
