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Comparison of rotavirus vaccines licensed in the United States

Comparison of rotavirus vaccines licensed in the United States
  Pentavalent human-bovine reassortant vaccine (RV5, PRV) Attenuated human rotavirus vaccine (RV1, HRV)
Trade name RotaTeq Rotarix
Serotypes contained G1, G2, G3, G4, P1[8] G1P[8]
Dose 2 mL 1 mL
Administration Ready-to-use Two formulations: one is ready to use; one requires reconstitution
Number of doses 3 2
Recommended schedule 2, 4, 6 months 2, 4 months
Minimum age first dose 6 weeks 6 weeks
Maximum age first dose
United States 14 weeks, 6 days 14 weeks, 6 days
Europe 12 weeks 12 weeks
Minimal interval between doses 4 weeks 4 weeks
Maximum age last dose
United States 8 months, 0 days 8 months, 0 days
Europe 24 weeks 24 weeks
Oral applicator Latex-free Contains latex*
Contains thimerosal No No
* Contraindicated in children with a severe (anaphylactic) allergy to latex.
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