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Systemic effects of elevated intra-abdominal pressure

Systemic effects of elevated intra-abdominal pressure
Central nervous system
↑ Intracranial pressure
↓ Cerebral perfusion pressure
Cardiac
Hypovolemia
↓ Cardiac output
↓ Venous return
↑ PCWP and CVP
↑ SVR
Pulmonary
↑ Intrathoracic pressure
↑ Peak inspiratory pressure
↑ Airway pressures
↓ Compliance
↓ PaO2
↑ PaCO2
↑ Shunt fraction
↑ Vd/Vt
Gastrointestinal
↓ Celiac blood flow
↓ SMA blood flow
↓ Mucosal blood flow
↓ pHi
Renal
↓ Urinary output
↓ Renal blood flow
↓ GFR
Hepatic
↓ Portal blood flow
↓ Mitochondrial function
↓ Lactate clearance
Abdominal wall
↓ Compliance
↓ Rectus sheath blood flow
Effects_of_ACS.htm
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