Central nervous system
|
↑ Intracranial pressure |
↓ Cerebral perfusion pressure |
Cardiac
|
Hypovolemia |
↓ Cardiac output |
↓ Venous return |
↑ PCWP and CVP |
↑ SVR |
Pulmonary
|
↑ Intrathoracic pressure |
↑ Peak inspiratory pressure |
↑ Airway pressures |
↓ Compliance |
↓ PaO2 |
↑ PaCO2 |
↑ Shunt fraction |
↑ Vd/Vt |
|
Gastrointestinal
|
↓ Celiac blood flow |
↓ SMA blood flow |
↓ Mucosal blood flow |
↓ pHi |
Renal
|
↓ Urinary output |
↓ Renal blood flow |
↓ GFR |
Hepatic
|
↓ Portal blood flow |
↓ Mitochondrial function |
↓ Lactate clearance |
Abdominal wall
|
↓ Compliance |
↓ Rectus sheath blood flow |
|