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Toxic granulations and Döhle bodies in infection/inflammation

Toxic granulations and Döhle bodies in infection/inflammation
(A) Peripheral blood smear shows neutrophils with toxic granulations, which are dark coarse granules. A Döhle body is also seen (arrow).
(B) A neutrophil with toxic granulations, vacuoles (another toxic change), and a Döhle body (arrow). These abnormalities are characteristic of toxic systemic illnesses.
Courtesy of Carola von Kapff, SH (ASCP).
Graphic 70248 Version 4.0