Regimens with activity against streptococci and staphylococci (MSSA) | |
Cephalexin or | |
Dicloxacillin or | |
Amoxicillin-clavulanate or | |
Clindamycin | |
Regimens with activity against streptococci and MRSA | |
Clindamycin* or | |
Linezolid or | |
Cephalexin or dicloxacillin PLUS Trimethoprim-sulfamethoxazole or doxycycline | |
Regimens with activity against streptococci, MRSA, aerobic gram-negative bacilli¶ and anaerobes | |
Trimethoprim-sulfamethoxazole PLUS Amoxicillin-clavulanate or Moxifloxacin -OR- | |
Clindamycin* PLUS Ciprofloxacin¶ or Levofloxacin¶ | |
Antibiotic dosing for adults with normal renal functionΔ | |
Cephalexin | 500 mg every 6 hours |
Dicloxacillin | 500 mg every 6 hours |
Clindamycin | 300 to 450 mg every 6 to 8 hours |
Linezolid | 600 mg every 12 hours |
Trimethoprim-sulfamethoxazole (co-trimoxazole) | 2 double-strength tablets (trimethoprim 160 mg and sulfamethoxazole 800 mg per tablet) every 12 hours |
Doxycycline | 100 mg orally every 12 hours |
Amoxicillin-clavulanate | 875/125 mg every 12 hours |
Ciprofloxacin | 500 mg every 12 hours (or, if there is concern for Pseudomonas aeruginosa, 750 mg every 12 hours) |
Levofloxacin | 500 mg every 24 hours (or, if there is concern for P. aeruginosa, 750 mg every 24 hours) |
Moxifloxacin◊ | 400 mg every 24 hours |