| Chelating agent | Adverse effects |
| BAL | |
| Endpoint: 24-hour urinary arsenic <50 mcg/L or until another agent is substituted | Hypertension Febrile reaction, diaphoresis Nausea, vomiting, salivation Lacrimation, rhinorrhea Headache Painful injection, injection site sterile abscess Hemolysis in G6PD-deficient patients Chelation of essential metals (prolonged course) |
| Succimer | |
| Endpoint: 24-hour urinary arsenic <50 mcg/L | Nausea, vomiting, diarrhea Abdominal gas, pain Transient elevations in hepatic amino transferases, and alkaline phosphatase Rash, pruritus Sore throat, rhinorrhea Drowsiness, paresthesias Thrombocytosis, eosinophilia |
| DMPS | |
| Endpoint: 24-hour urinary arsenic <50 mcg/L | Allergic reactions Increased copper and zinc excretion Nausea Pruritus Vertigo Weakness |
