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Examples of oxytocin infusion protocols

Examples of oxytocin infusion protocols
Regimen Starting dose (milliunits/minute) Incremental increase (milliunits/minute) Dose interval (minutes)
Low-dose 0.5 to 1 1 30 to 40
Alternative low-dose 1 to 2 1 to 2 15 to 30
High-dose 6

6

The incremental increase should be reduced to 3 milliunits/minute if hyperstimulation is present and reduced to 1 milliunit/minute if recurrent hyperstimulation		 15 to 40
Some clinicians limit to a maximum cumulative dose of 10 units and a maximum duration of 6 hours
Alternative high-dose 4 4 15
Oxytocin should be administered by trained personnel who are familiar with its effects. It should be administered using an infusion pump that provides precise flow rate to ensure accurate minute-to-minute control. Most clinicians will not administer more than 40 milliunits/minute as the maximum dose.
Sample oxytocin infusion protocols courtesy of author with additional information from ACOG Committee on Practice Bulletins – Obstetrics, ACOG Practice Bulletin No. 107: Induction of Labor. Obstet Gynecol 2009; 114:386 (reaffirmed 2020).
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