| Historical feature | Possible significance |
| Daytime symptoms | Dysfunctional voiding |
| Lower urinary tract symptoms (voiding ≥8 or ≤3 times per day, hesitancy, straining, weak stream, intermittent stream, incomplete emptying, postmicturition dribble, genital or lower urinary tract pain) | Dysfunctional voiding or anatomic abnormality (eg, posterior urethral valves) |
| Prolonged period of dryness (>6 months) | Secondary enuresis more often associated with psychologic comorbidities |
| Frequency of episodes | Nightly enuresis is associated with persistence |
| Change in frequency of episodes over time | The natural history is of spontaneous resolution |
| Approximate volume of enuretic void | Estimate of bladder capacity |
| Fluid intake diary | May suggest etiology of nocturnal polyuria (increased afternoon/evening fluid intake; diabetes mellitus; diabetes insipidus; psychogenic polydipsia) |
| Stooling history | Constipation may contribute to decreased bladder capacity |
| Review of systems | May identify previously undiagnosed medical condition that contributes to enuresis |
| - Snoring | - Obstructive sleep apnea |
| - Weight loss, fatigue | - Diabetes, kidney disease |
| - Gait abnormalities | - Spinal dysraphism |
| - Staring spells | - Seizure disorder |
| - Perianal itching, vulvovaginitis | - Pinworms |
| - Excessive thirst, nighttime drinking | - Diabetes, kidney disease, psychogenic polydipsia |
| Family history of enuresis | Genetic factors may be contributing |
