Prevalence of thrombophilic defects in venous thrombosis
Prevalence of thrombophilic defects in venous thrombosis
Condition
Prevalence, percent*
Activated protein C resistance (factor V Leiden)
12 to 40¶
Prothrombin G20210A gene mutation
6 to 18¶
Deficiencies of Antithrombin, protein C, protein S
5 to 15
Antiphospholipid antibody syndrome
5 to 10
* Note: The lower percentage for each condition is for unselected patients; the higher percentage is for those with first events prior to age 50 or with a history of venous thrombosis in first-degree relatives. ¶ Prevalence restricted to White populations.