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Acceptable, borderline, and abnormal plasma lipid, lipoprotein, and apolipoprotein concentrations for children and adolescents

Acceptable, borderline, and abnormal plasma lipid, lipoprotein, and apolipoprotein concentrations for children and adolescents
Category Acceptable
mg/dL (mmol/L)		 Borderline
mg/dL (mmol/L)

High
mg/dL (mmol/L)
TC <170 (4.4) 170 to 199 (4.4 to 5.2) ≥200 (5.2)
LDL-C <110 (2.8) 110 to 129 (2.8 to 3.3) ≥130 (3.4)
Non-HDL-C <120 (3.1) 120 to 144 (3.1 to 3.7) ≥145 (3.8)
ApoB <90 (2.3) 90 to 109 (2.3 to 2.8) ≥110 (2.8)
TG
• 0 to 9 years <75 (0.8) 75 to 99 (0.8 to 1.1) ≥100 (1.1)
• 10 to 19 years <90 (1 mmol/L) 90 to 129 (1 to 1.5) ≥130 (1.5)
Category

Acceptable
mg/dL (mmol/L)

Borderline
mg/dL (mmol/L)

Low
mg/dL (mmol/L)
HDL-C >45 (1.2) 40 to 45 (1 to 1.2) <40 (1)
ApoA-1 >120 (3.1) 115 to 120 (3 to 3.1) <115 (3)
Values for plasma lipid and lipoprotein levels are from the National Cholesterol Education Program (NCEP) Expert Panel on Cholesterol Levels in Children. Non-HDL-C values from the Bogalusa Heart Study are equivalent to the NCEP Pediatric Panel cut points for LDL-C. Values for plasma ApoB and ApoA-1 are from the National Health and Nutrition Examination Survey III (NHANES III). The threshold points for high and borderline-high values represent approximately the 95th and 75th percentiles, respectively. Low threshold points for HDL-C and ApoA-1 represent approximately the 10th percentile.
TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; ApoB: apolipoprotein B; TG: triglycerides; ApoA-1: apolipoprotein A-1.
Reproduced from: Daniels SR, Benuck I, Christakis DA, et al. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: Full report, 2011. National Heart Lung and Blood Institute. Available at: http://www.nhlbi.nih.gov/guidelines/cvd_ped/peds_guidelines_full.pdf.
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