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Proposed classification systems for ductal carcinoma in situ

Lagios*	Van Nuys•	EuropeanΔ
Low grade	Non-high grade without necrosis	Well differentiated
Intermediate grade	Non-high grade with necrosis	Intermediately differentiated
High grade	High grade	Poorly differentiated

Classification_of_DCIS.htm

* Adapted from Lagios MD, Margolin FR, Westdahl PR, Rose MR. Cancer 1989; 63:618.
• Silverstein MJ, Poller DN, Waisman JR, et al. Lancet 1995; 345:1154.
Δ Holland R, Peterse JL, Millis RR, et al. Semin Diagn Pathol 1994; 11:167.

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