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Patterns of thyroid function tests during assessment of thyroid function

Patterns of thyroid function tests during assessment of thyroid function
Serum TSH Serum free T4 Serum T3 Assessment
Normal hypothalamic-pituitary function
Normal Normal Normal Euthyroid
Normal Normal or high Normal or high Euthyroid hyperthyroxinemia
Normal Normal or low Normal or low Euthyroid hypothyroxinema
Normal Low Normal or high Euthyroid: T3 therapy
Normal Low-normal or low Normal or high Euthyroid: thyroid extract therapy
High Low Normal or low Primary hypothyroidism
High Normal Normal Subclinical hypothyroidism
Low High or normal High Hyperthyroidism
Low Normal Normal Subclinical hyperthyroidism
Abnormal hypothalamic-pituitary function
Normal or high High High TSH-mediated hyperthyroidism
Normal or low* Low or low-normal Low or normal Central hypothyroidism
T3: triiodothyronine; T4: thyroxine; TSH: thyroid-stimulating hormone.
* In central hypothyroidism, serum TSH may be low, normal, or slightly high.
Graphic 67935 Version 4.0