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Microdeletion FISH

Microdeletion FISH
FISH of a patient with a deletion of chromosome 22q, the DiGeorge/VCF syndrome. As shown, the VCF probe only hybridizes with one chromosome 22 (red line and arrows). By comparison, the fluorescent green probe is a control probe that hybridizes to both chromosomes.
FISH: fluorescence in situ hybridization; VCF: velocardiofacial.
Graphic 67440 Version 3.0