| Topical preparation | Brand name (United States) | Antiseptic | Glucocorticoid | pH | Preservative | Notes |
| Acidifying/antiseptic solution | ||||||
| Acetic acid 2% otic solution | Generic (formerly Acetasol) | Acetic acid | None | 3.5 to 5 | No additional | Avoid use of acidifying antiseptic agents if tympanic membrane is known or suspected to be non-intact; contains boric acid |
| Acidifying/antiseptic and glucocorticoid combination | ||||||
| Acetic acid 2% and hydrocortisone 1% otic solution | Acetasol HC, VoSol HC otic | Acetic acid | Hydrocortisone | 2 to 4 | No additional | Avoid use of acidifying antiseptic agents if tympanic membrane is known or suspected to be non-intact; contains propylene glycol (drying agent) and benzethonium for promoting tissue penetration |
| Antibiotic and glucocorticoid combinations | ||||||
| Ciprofloxacin 0.3% and dexamethasone 0.1% otic suspension | Ciprodex | None | Dexamethasone | Buffered | Benzalkonium chloride | Contains boric acid |
| Ciprofloxacin 0.2% and hydrocortisone 1% otic suspension | Cipro HC otic | None | Hydrocortisone | Buffered | Benzyl alcohol | |
| Neomycin 0.35%, polymyxin B 10,000 units/mL, and hydrocortisone 0.5% otic solution | Cortisporin otic | None | Hydrocortisone | Acidic | Potassium metabisulfite | Avoid use of topical aminoglycosides if tympanic membrane is known or suspected to be non-intact |
| Neomycin 0.33%, colistin 0.3%, and hydrocortisone 1% otic suspension | Coly-Mycin S, Cortisporin TC | None | Hydrocortisone | 5 | Thimerosal | Avoid use of topical aminoglycosides if tympanic membrane is known or suspected to be non-intact; contains thonzonium for promoting tissue penetration |
| Gentamicin 0.3% and prednisolone 1% ophthalmic suspension¶ | Pred-G | None | Prednisolone | 5.4 to 6.6 | Benzalkonium chloride | Avoid use of topical aminoglycosides if tympanic membrane is known or suspected to be non-intact |
| Tobramycin 0.3% and dexamethasone 0.1% ophthalmic suspension¶ | TobraDex | None | Dexamethasone | Buffered | Benzalkonium chloride | Avoid use of topical aminoglycosides if tympanic membrane is known or suspected to be non-intact |
| Gentamicin 0.3% and betamethasone 0.1% otic solution | GarasoneΔ (not available in United States) | None | Betamethasone | Buffered | Benzalkonium chloride | Avoid use of topical aminoglycosides if tympanic membrane is known or suspected to be non-intact; contains boric acid |
| Antibiotic | ||||||
| Solutions | ||||||
| Ciprofloxacin 0.2% otic solution | Cetraxal otic | None | None | Buffered | None; single-use container | Supplied as 0.5 mg per 0.25 mL individual use containers; contains povidone |
| Ofloxacin 0.3% otic solution | Generic (formerly Floxin otic) | None | None | 6.5 | Benzalkonium chloride | |
| Health care provider-administered suspension | ||||||
| Ciprofloxacin 6% otic suspension | Otiprio | None | None | Buffered | None; single-use container | Prepared and administered by health care provider as a single 0.2 mL (12 mg) dose to external ear canal of each affected ear Costlier than most other options |
| Glucocorticoid suspension | ||||||
| Dexamethasone 0.1% ophthalmic suspension¶ | Maxidex | None | Dexamethasone | Buffered | Benzalkonium chloride | |
