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Predictive variables of outcome after hematopoietic cell transplantation in pediatric patients with thalassemia

Predictive variables of outcome after hematopoietic cell transplantation in pediatric patients with thalassemia
Risk factor Adverse Favorable
Hepatomegaly (cm from costal arch) >2 cm ≤2 cm
Liver fibrosis Presence Absence
Iron chelation therapy Irregular Regular
Risk class
Class I patients have all three favorable risk factors
Class II patients have one or two adverse risk factors
Class III patients have all three adverse risk factors
Refer to UpToDate topics on HCT for thalassemia and iron chelation therapy for details.
HCT: hematopoietic cell transplantation.
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