Relative risk versus absolute risk estimates of fracture
Relative risk versus absolute risk estimates of fracture
Age
Hip T-score
Relative risk
10-year fracture probability (%)
50
–2.5
17.6
1.7
80
–2.5
17.6
11.5
Relative risk compared with age-matched females with normal BMD.
(RR per SD change in BMD)T-score Difference = (2.6)2.5 = 17.6.
BMD: bone mineral density; RR: relative risk; SD: standard deviation.
10-year fracture probability from Swedish National Bureau of Statistics.
Data from: Marshall D, Johnell O, Wedel H. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 1996; 312:1254 and Kanis JA, Johnell O, Oden A, et al. Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds. Osteoporosis International 2001; 12:989.