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Risk of childhood leukemia after in utero exposure to radiation compared to other risk groups

Risk of childhood leukemia after in utero exposure to radiation compared to other risk groups
Group Approximate risk Increase in risk above baseline
Identical twin of leukemic twin 1/3 1000
Irradiation-treated polycythemia 1/6 500
Bloom syndrome 1/8 375
Hiroshima survivors who were within 1000 meters of the hypocenter 1/60 50
Down's syndrome 1/95 30
Irradiation-treated ankylosing spondylitis 1/270 10
Siblings of leukemic children 1/720 4
Children exposed to in-utero pelvimetry 1/2000 1.5
US White children <15 years old 1/2800 1
Data from: Miller RW. Epidemiologic conclusions from radiation toxicity studies. In: Late Effects of Radiation, Fry, RJM,Grahn, D, Griem, ML, et al (Eds). Taylor and Francis, London, 1970.
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