your limit has been reached. plz Donate us to allow your ip full access, Email: sshnevis@outlook.com
Uptodate Reference Title
Acute promyelocytic leukemia
Acute promyelocytic leukemia
During treatment with tretinoin, malignant promyelocytes in acute promyelocytic leukemia (APL) begin to differentiate to neutrophils. The cells acquire secondary granules, and the nuclear chromatin becomes condensed.