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Select drugs that have been documented NOT to interact with theophylline or NOT to have clinically important interactions with theophylline

Select drugs that have been documented NOT to interact with theophylline or NOT to have clinically important interactions with theophylline
Amoxicillin Medroxyprogesterone
Ampicillin, with or without sulbactam Methylprednisolone
Atenolol Metronidazole
Azithromycin Metoprolol
Cefaclor Nifedipine
Co-trimoxazole (trimethoprim and sulfamethoxazole) Nizatidine
Diltiazem Ofloxacin
Famotidine Omeprazole
Felodipine Paroxetine
Fluoxetine Prednisone, prednisolone
Finasteride Ranitidine*
Hydrocortisone Rifabutin
Isoflurane Roxithryomycin
Isradipine Sertraline
Influenza vaccine Sorbitol (purgative doses do not inhibit theophylline absorption)
Ketoconazole Sucralfate
Lomefloxacin Terfenadine
Mebendazole Tetracycline
This is not a complete list. When initiating or altering drug therapy, use of a drug interactions database, such as Lexicomp drug interactions, is advised.
* This medication has been withdrawn from the market in the United States.
Adapted from: Hendeles L, Jenkins J, Temple R. Revised FDA labeling guideline for theophylline oral dosage forms. Pharmacotherapy 1995; 15:409.
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