| Clinical manifestations |
| Edema |
| Ascites |
| Pleural effusion |
| Pericardial effusion |
| Laboratory abnormalities |
| Hypoalbuminemia without proteinuria, disorders associated with decreased protein synthesis, or malnutrition |
| Reduced plasma concentrations of: |
| Gamma globulins |
| Cholesterol |
| Alpha-1 antitrypsin |
| Fibrinogen |
| Ceruloplasmin |
| Lymphopenia |
| Malabsorption of fat and fat-soluble vitamins |
