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Results of whole breast irradiation for node-positive occult primary breast cancer

Author, year	Number of patients	Median follow-up	Breast treatment	Breast-only control, percent	Survival (percent)
Vilcoq J; 1982	11	>5 yr	XRT	73	10/11 (5 year)
Ellerbroek N; 1990	16	133 months	XRT	83	–*
	13		None	43	–*
	13		Mastectomy	N/A	–*
Foroudi F; 2000	12	73 months	XRT	75	11/12 (5 year)
Vlastos G; 2001	25	7 years	XRT	92	79 percent (5 year)
Vlastos G; 2001	13	7 years	Mastectomy	85	75 percent (5 year)
Medina-Franco H; 2002	6	48 months	XRT	100	100 percent
Varadarajan R; 2006	8	57 months	XRT	100	100 percent
He D; 2012	95	38.2 months	Mastectomy + ALND^¶	89	85 (3 year)
			Breast XRT + ALND	92	81
			ALND	72	71

XRT: whole breast radiation therapy; N/A: not available.
* Survival described as "no different" when patients undergoing mastectomy were compared to those who did not undergo mastectomy. Actuarial survival for entire group was 72 percent at five years and 65 percent at 10 years.
¶ ALND: axillary lymph node dissection.

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