Disorder | Serum phosphate | Serum calcium | Serum alkaline phosphatase | Parathyroid hormone | 25-hydroxyvitamin D | 1,25-dihydroxyvitamin D |
Vitamin D deficiency | ↓ or N | ↓ or N | ↑ | ↑ | ↓↓ | N or ↑ or ↓ |
Conditions associated with urinary phosphate wasting | ↓↓ | N | N or ↑ | N | N | N |
Proximal renal tubular acidosis | ↓ | N | N | N | N | N |
Hypophosphatasia | N | N | ↓ | N | N | N |
Osteogenesis imperfecta and axial osteomalacia | N | N | N or ↑ | N | N | N |
Osteoporosis | N | N | N | N | N or ↓ | N |