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Leptomeningeal metastasis from malignant melanoma

Leptomeningeal metastasis from malignant melanoma
A)Pigmented tumor cells are seen filling the subarachnoid space over the convexity of the brain. B) The tumor cells fill the subarachnoid space (1), have grown down the Virchow-Robin spaces into the brain (2) and have breached that space to invade the brain (3).
Courtesy of Alexis Demopoulos, MD, and Jerome Posner, MD.
Graphic 65372 Version 2.0