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T3-resin test in TBG deficiency

T3-resin test in TBG deficiency
The radiolabeled T3 (*T3) cannot bind to diminished or absent TBG; as a result, the amount left over to bind to the resin is higher than normal. The serum total T4 is low; the T3-resin uptake and THBR are high, and the serum free T4 index is normal.
T3: triiodothyronine; T4: thyroxine; TBG: thyroxine-binding globulin; THBR: thyroid hormone binding ratio.
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