Abnormally large, bizarre osteoclasts characterize pagetic bone. There is thickened trabeculae on this H&E stain, with the bone rimmed with osteoblasts and the marrow replaced by stromal cells. Pagetic bone is extremely vascular.
H&E: hematoxylin and eosin.
Reproduced with permission from: the Paget Foundation. For more information please visit http://www.paget.org/.
