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Clinical spectrum of fusariosis

Clinical spectrum of fusariosis
Immunocompetent hosts
Non-infectious
Mycotoxicosis
Allergic bronchopulmonary fusariosis
Infectious
Common:
Onychomycosis
Keratitis*
Uncommon:
Cutaneous (burns, wounds)[1]
Peritonitis (patients receiving CAPD)[2-4]
Endocarditis
Pneumonia
Sinusitis
Endophthalmitis
Thrombophlebitis
Fungemia
Arthritis
Immunocompromised hosts[5]
Invasive infection
Disseminated
Multiorgan infection
Isolated fungemia
Localized
Common:
Cellulitis
Sinusitis
Pneumonia
Less common:
CNS infection
Endophthalmitis
Arthritis/osteomyelitis
CAPD: continuous ambulatory peritoneal dialysis; CNS: central nervous system.
* Outbreaks of fusarial keratitis have been reported among contact lens wearers[6].
References:
  1. Nucci M, Anaissie E. Cutaneous infection by Fusarium species in healthy and immunocompromised hosts: implications for diagnosis and management. Clin Infect Dis 2002; 35:909.
  2. Rippon JW, Larson RA, Rosenthal DM, Clayman J. Disseminated cutaneous and peritoneal hyalohyphomycosis caused by Fusarium species: three cases and review of the literature. Mycopathologia 1988; 101:105.
  3. Kerr CM, Perfect JR, Craven PC, et al. Fungal peritonitis in patients on continuous ambulatory peritoneal dialysis. Ann Intern Med 1983; 99:334.
  4. Flynn JT, Meislich D, Kaiser BA, et al. Fusarium peritonitis in a child on peritoneal dialysis: case report and review of the literature. Perit Dial Int 1996; 16:52.
  5. Nucci M, Anaissie E. Fusarium infections in immunocompromised patients. Clin Microbiol Rev 2007; 20:695.
  6. Patel A, Hammersmith K. Contact lens-related microbial keratitis: recent outbreaks. Curr Opin Ophthalmol 2008; 19:302.
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