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Uptodate Reference Title
Explanatory mechanisms for persistent diarrhea
Explanatory mechanisms for persistent diarrhea
Several different mechanisms can explain the development of persistent diarrhea following an episode of acute diarrhea:
A secondary event such as lactose intolerance or bacterial overgrowth develops during the acute episode and causes the symptoms to persist.
Because of special pathogen characteristics, the infectious agent is never cleared and causes prolonged illness.
Because of weakness in defenses (eg, immunosuppression or poor intestinal regeneration), the host is unable to efficiently clear the pathogen and recovery is delayed.
Multiple new infections with separate pathogens cause continued symptoms.
