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Uptodate Reference Title
Creation of a congenic strain
Creation of a congenic strain
A highly schematic representation of the relative contributions of donor and recipient alleles at sequential generations of backcrossing. The donor contribution is indicated in white and the recipient contribution is indicated in black with the checkerboard pattern indicative of heterozygous loci. By the tenth generation of backcrossing, the differential segment around the selected locus will represent the major contribution from the donor genome.
Reproduced with permission from Professor Lee M. Silver, Princeton University, for use of this illustration, which appeared originally in "Mouse Genetics," published in hardcopy by Oxford University Press, and online by the Jackson Laboratory (http://www.jax.org).
