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Immunofluorescence microscopy of glomerular capillaries showing location of IgG

Immunofluorescence microscopy of glomerular capillaries showing location of IgG
(A) Circulating anti-GBM antibodies with linear immunofluorescence staining of GBM.
(B) Glomerular immune complex localization with granular immunofluorescence staining.
(C) Circulating ANCA with paucity of glomerular immunofluorescence immunoglobulin staining.
IgG: immunoglobulin G; GBM: glomerular basement membrane; ANCA: antineutrophil cytoplasmic autoantibodies.
Courtesy of J Charles Jennette, MD.
Graphic 63060 Version 5.0