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Radiation toxicity: Cutaneous system

Radiation toxicity: Cutaneous system
Symptom/sign Degree 1 Degree 2 Degree 3 Degree 4
Erythema Minimal, transient Moderate <10% BSA Marked 10 to 40% BSA Severe >40% BSA
Sensation/itching Pruritus Slight, int. pain Moderate persistent pain Severe persistent pain
Blistering Rare Rare hemorrhage Bullae Bullae hemorrhage
Desquamation Absent Patchy, dry Patchy, moist Confluent, moist
Ulcer/necrosis Epidermal only Dermal Subcutaneous Muscle or bone
Onycholysis Absent Partial Partial Complete
BSA: body surface area; int: intermittent.
Modified with permission from: Waselenko JK, MacVittie TJ, Blakely WF, et al. Medical management of the acute radiation syndrome: Recommendations of the strategic national stockpile radiation working group. Ann Intern Med 2004; 140:1037. Copyright © 2004 American College of Physicians.
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