1, 6 | Doxorubicin | 37.5 mg/m2 per day by continuous IV infusion or IV push | 1 and 2 |
Cisplatin | 60 mg/m2 per day IV over four hours | 1 and 2 |
12, 17 | DoxorubicinΔ | 37.5 mg/m2 per day by continuous IV infusion or IV push | 1 and 2 |
Cisplatin | 60 mg/m2 per day IV over four hours | 1 and 2 |
15, 16, 20, 21, 24, 25, 28, 29 | High-dose methotrexate | 12 grams/m2 IV over four hours | 1 |
Leucovorin rescue | 15 mg (approximately 10 mg/m2) every six hours IV or orally for 10 doses | Starting 24 hours after beginning high-dose methotrexate |