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Bone marrow – ring sideroblasts

Bone marrow – ring sideroblasts
(A) Bone marrow aspirate stained with Prussian blue to show red cell precursors with numerous iron-positive granules surrounding the nucleus, in some cases forming a complete ring (arrows).
(B) Electron micrograph of a single erythroblast with iron-laden mitochondria (electron-dense deposits and thick arrows) clustered near its nucleus.
Courtesy of Sylvia Bottomley, MD.
Graphic 62536 Version 4.0