| System | Manifestations |
| Neurologic | Anencephaly with or without herniation of neural elements, arrhinencephaly, microcephaly, holoprosencephaly, neural tube defects (meningomyelocele and other variants). |
| Cardiovascular | Transposition of the great vessels with or without ventricular septal defect (VSD), VSD, coarctation of the aorta with or without VSD or patent ductus arteriosus, atrial septal defect, single ventricle, hypoplastic left ventricle, pulmonic stenosis, pulmonary valve atresia, double outlet right ventricle truncus arteriosus. |
| Gastrointestinal | Duodenal atresia, imperforate anus, anorectal atresia, small left colon syndrome, situs inversus. |
| Genitourinary | Ureteral duplication, renal agenesis, hydronephrosis. |
| Skeletal | Caudal regression syndrome (sacral agenesis), hemivertebrae. |
| Other | Single umbilical artery. |
