Medication | Minimum time to omit medication before challenge tests |
Inhaled bronchodilators |
Albuterol | 8 hours |
Levalbuterol | 8 hours |
Terbutaline | 8 hours |
Formoterol, salmeterol | 36 hours |
Ultra long-acting beta agonists (eg, indacaterol, olodaterol, vilanterol) | 48 hours |
Short-acting muscarinic antagonist (ipratropium) | 12 hours |
Long-acting muscarinic antagonists (aclidinium, glycopyrrolate, tiotropium) | 72 hours |
Oral theophylline | 24 hours |
Oral albuterol | 12 to 24 hours |
Inhaled glucocorticoid (budesonide, fluticasone propionate)* | 6 hours |
Inhaled glucocorticoid (long acting; fluticasone furoate, ciclesonide) | 24 hours |
Oral glucocorticoid* | 2 to 3 weeks |
Cromolyn sodium¶ | 4 hours |
Antihistamines (cetirizine, fexofenadine, loratadine) | 72 hoursΔ |
Leukotriene modifiers |
Montelukast◊ | 4 days |
Zafirlukast | 4 days |