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Uptodate Reference Title
Resumption of the steady state in primary aldosteronism
Resumption of the steady state in primary aldosteronism
The combination of aldosterone administration and the ingestion of a high Na+ diet leads initially to Na+ retention, volume expansion, and a rise in systemic blood pressure. After several days, however, there is a spontaneous diuresis, resulting in the return of Na+ balance toward normal but persistent hypertension.