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Uptodate Reference Title
Prolongation of reticulocyte maturation time in anemia
Prolongation of reticulocyte maturation time in anemia
With worsening anemia and increasing erythropoietin stimulation, bone marrow reticulocytes (left) leave the marrow at an earlier stage in their maturation. This prolongs the maturation time in the circulation from one day to as long as 2.5 days (right).
Adapted from: Normal erythropoiesis. In: Hematology in Clinical Practice, Hillman RS, Ault KA (Eds), McGraw-Hill, New York. p.29.
