Age at first stroke and cumulative incidence of stroke in SCD according to genotype

Age at first stroke (ischemic or hemorrhagic) and cumulative incidence of stroke in 2436 patients with sickle cell disease. The graph shows the percentage of individuals without a stroke. These data largely represent patients who did not receive primary prevention. The number of patients in each genotype is as follows: HbSS, 2346; HbS-beta⁰ thalassemia, 188; HbS-beta⁺ thalassemia, 184; HbSC, 839.