| Class Ia drugs |
| At least 1 case report with positive rechallenge, excluding all other causes, such as alcohol, hypertriglyceridemia, gallstones, and other drugs |
| Class Ib drugs |
| At least 1 case report with positive rechallenge; however, other causes, such as alcohol, hypertriglyceridemia, gallstones, and other drugs were not ruled out |
| Class II drugs |
| At least 4 cases in the literature |
| Consistent latency (≥75 percent of cases) |
| Class III drugs |
| At least 2 cases in the literature |
| No consistent latency among cases |
| No rechallenge |
| Class IV drugs |
| Drugs not fitting into the earlier-described classes, single case report published in medical literature, without rechallenge |
