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Histologic appearance of meningioma, WHO grades 1-3

Histologic appearance of meningioma, WHO grades 1-3
(A) Transitional meningioma (grade 1) showing characteristic cellular whorls; intranuclear pseudo-inclusions are visible in some cells.
(B) Chordoid meningioma (grade 2) with cohesive epithelial-like cords of cells; small foci of more typical arachnoidal differentiation are found in most of these tumors.
(C) Anaplastic meningioma (grade 3) consisting of pleomorphic arachnoidal cells with a high mitotic rate; foci of necrosis are widely distributed throughout most anaplastic meningiomas.
Reproduced with permission from: Whittle IR, Smith C, Navoo P, Collie D. Meningiomas. The Lancet 2004; 363:1536. Copyright © 2004 Elsevier.
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