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Uptodate Reference Title
Methacholine challenge testing sequence
Methacholine challenge testing sequence
* The choice of the FEV1 value considered a contraindication may vary from 60 to 70% of predicted. An FEV1 <1.5 L in adults is an additional contraindication. ¶ 400 microg is roughly equivalent to 16 mg/mL. Δ The final dose may vary depending on the dosing schedule used. Final doses discussed in this statement are 16, 25, and 32 mg/mL.
Reference: Coates AL, Wanger J, Cockcroft DW, et al. ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests. Eur Respir J 2017; 49.
