| Increase CNIs | Decrease CNIs |
| Diltiazem (potent) | Carbamazepine |
| Verapamil (potent) | Rifabutin |
| Fluconazole (potent) | Phenobarbital |
| Erythromycin | Caspofungin |
| Ketoconazole (potent) | Phenytoin |
| Voriconazole (potent) | Rifampin |
| Nicardipine | St. John's Wort |
| Clotrimazole | Sirolimus |
| Nifedipine (mild effect) | |
| Itraconazole | |
| Troleandomycin | |
| Clarithromycin |
